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Neurobiology

๐Ÿง  Subject Overview: Neurobiology

Neurobiology is the study of the nervous system, encompassing the molecular biophysics of excitable membranes, synaptic chemical neurotransmission, circuit computation, sensory transduction, and the molecular mechanisms of synaptic plasticity and neurodegeneration.

Curriculum & Syllabus Roadmap

This master syllabus organizes neurobiology into 5 core academic modules, complete with mathematical formulations, vector biophysical diagrams, and clinical pharmacological correlations.

Unit I • Biophysics

Action Potential & Ion Channels

Resting membrane potential, GHK equation, Hodgkin-Huxley model, voltage-gated Na+/K+ channel kinetics, and saltatory conduction.

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Unit II • Synapses

Synaptic Transmission & Neurotransmitters

SNARE-mediated exocytosis, quantal neurotransmitter release, ionotropic vs metabotropic receptors, EPSPs, IPSPs, and summation.

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Unit III • Sensory

Sensory Systems & Phototransduction

Photoreceptor physiology, rhodopsin-transducin cascade, auditory stereocilia tip-link transduction, and sensory coding.

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Unit IV • Motor Control

Neuromuscular Junction & Motor Systems

Motor endplate anatomy, acetylcholine receptor channels, T-tubule DHPR/RyR1 coupling, and spinal reflex circuits.

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Unit V • Plasticity

Neural Plasticity & Long-Term Potentiation

Hebbian synapses, NMDA/AMPA receptor trafficking, CaMKII activation, dendritic remodeling, and neurodegenerative pathology.

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